Program Schedule
| September 16th, Saturday | ||
|---|---|---|
| 8:30 | Light Breakfast | |
| 9:00 | Welcome (Sudhir Kumar) | |
| Monogenic Diseases | ||
| 9:15 | Yana Bromberg | Improving variant effect prediction: function, disease, and evolution of “normal” |
| 9:45 | Eduardo G. Amorim | The population genetics of Mendelian diseases: the case of recessive, lethal mutations |
| 9:55 | Jinchuan Xing | Investigate lysosomal disease etiology by exome sequencing |
| 10:05 | Jody Hey | A new method for identifying young, harmful mutations in human populations |
| 10:15 | Laura Scheinfeldt | Ancient Adaptive landscape of the human exome |
| 10:25 | Coffee Break | |
| Cancer Evolution | ||
| 11:00 | Jeff Townsend | Population genetics of selection on somatic variants in cancer: identifying therapeutic targets and predicting evolution of resistance to therapy |
| 11:30 | Sayaka Miura | Discovering tumor clones using molecular phylogenetics |
| 11:50 | Vincent Cannataro | The likelihood of heterogeneity or additional mutation in KRAS or associated oncogenes to compromise targeting of oncogenic KRAS G12C |
| 12:00 | Kshitiz | How Evolution of Pregnancy May Have Solved the Problem for Cancer Malignancy |
| 12:10 | Lunch Served | |
| Complex Diseases | ||
| 1:30 | Joel Dudley | Using evolutionary genomics to inform precision medicine discovery |
| 2:00 | Li Liu | Fast Fine Mapping of Causal eQTL Variants |
| 2:10 | Katherine Siewert | Two signals of balancing selection localizing with complex trait loci |
| 2:20 | David Liberles | Context dependence of the functional effects of SNPs: a pathway simulation approach |
| 2:30 | Josh Akey | Signatures of recent widespread relaxation of functional constraint in protein-coding genes |
| 3:00 | Coffee Break | |
| Infectious Diseases | ||
| 3:30 | Sarah Tishkoff | Evolution and Adaptation in Africa: Implications for Health and Disease |
| 4:00 | Ananias Escalante | Origins of Human malaria |
| 4:10 | Fabia Battistuzzi | Evolution Of Low Complexity Regions In Plasmodium |
| 4:20 | Joshua P. Earl | Comparison of Two Machine Learning Techniques to Predict Virulence, and Habitat of Non-Typeable Haemophilus influenzae Via Gene Possession |
| 4:30 | Chase Nelson | Virus-host coevolution and carcinogenicity through the lens of human papillomavirus |
| . | ||
| 4:40 | Randy Nesse | Selection shapes fitness cliffs that cause disease vulnerability |
| 5:10 | Reception | |
| 5:10 | Poster Session | |
| September 17th, Sunday | ||
|---|---|---|
| 8:30 | Light Breakfast | |
| 9:00 | Introduction (Sudhir Kumar) | |
| Molecular Phylogenetics | ||
| 9:15 | Claudia Russo | Diversification of major groups of birds |
| 9:45 | Saitou Naruya | 30 year anniversary of the Neighbor-Joining method |
| 9:52 | Koichiro Tamura | RelTime: divergence time estimation under evolutionary rate variation |
| 9:59 | Naoko Takezaki | Resolving the Phylogenetic Position of Coelacanth: The Closest Relative Is Not Always the Most Appropriate Outgroup |
| 10:06 | S. Blair Hedges | Evolutionary Timetrees |
| 10:13 | Ruriko Yoshida | Principal Component Analysis in the Space of Phylogenetic Trees |
| 10:20 | Sabayasachi Das | A Phylogenetic Journey Through Adaptive Immunity |
| 10:27 | Kazuharu Misawa | The Continuous Isolation-By-Distance Model Explains Why Genes Mirror Geography |
| 10:32 | Coffee Break | |
| Functional Evolution - I | ||
| 11:03 | Wen-Hsiung Li | Evolutionary approach to functional genomics |
| 11:33 | Jongmin Nam | Can sea urchins find human embryonic enhancers and promoters? |
| 11:41 | Helen Piontkivska | Role of Host Immunity in Zika-Mediated Pathogenesis |
| 11:49 | Wojciech Makalowski | Evolutionary value of junk DNA |
| 11:57 | Zhenguo Zhang | Drosophila X-Linked Genes Have Lower Translation Rates Than Autosomal Genes |
| 12:05 | Shozo Yokoyama | Far-red and green color vision in the dark deep-sea |
| 12:13 | Nikolas Nikolaidis | Decoding the human cellular stress response |
| 12:21 | Lunch Served | |
| Population Genetics | ||
| 1:31 | Aravinda Chakravarti | The molecular and population genetics of a complex disorder |
| 2:01 | Joaquin Dopazo | A look at the human mutational load from the systems biology perspective |
| 2:09 | Marcy Uyenoyama | Extending the Ewens Sampling Formula to structured populations |
| 2:17 | Dimitra Chalkia | Autism Spectrum Disorders: certainly complex, probably with a mitochondrial twist |
| 2:25 | Partha Majumder | Revisiting "Genetic Relationships between Indians and Their Neighboring Populations" Thirty-two Years Later |
| 2:55 | Coffee Break | |
| Functional Evolution - II | ||
| 3:28 | George Zhang | Evolutionary adaptations to new environments generally reverse plastic phenotypic changes |
| 3:58 | Zhenguo Lin | Evolutionary dynamics of transcription initiation in yeasts |
| 4:06 | Masafumi Nozawa | Accelerated pseudogenization on the neo-X chromosome in Drosophila miranda |
| 4:14 | Igor Rogozin | Evolutionary switches between two serine codon series are driven by selection |
| 4:22 | Li Hao | Molecular epidemiology and evolutionary dynamics of Neisseria meningitidis |
| 4:30 | Takashi Gojobori | Comparative Marine Metagenomics with Micro-Fluidics of Single-Cell Screening |
| 5:00 | Nei Associates Meet at Lobby | |
| September 16th, Saturday | ||
|---|---|---|
| 8:30 | Light Breakfast | ||
| 9:00 | Welcome (Sudhir Kumar) | ||
| Monogenic Diseases | ||
| 9:15 | Yana Bromberg | ||
| Improving variant effect prediction: function, disease, and evolution of “normal” | ||
| 9:45 | Eduardo G. Amorim | ||
| The population genetics of Mendelian diseases: the case of recessive, lethal mutations | ||
| 9:55 | Jinchuan Xing | ||
| Investigate lysosomal disease etiology by exome sequencing | ||
| 10:05 | Jody Hey | ||
| A new method for identifying young, harmful mutations in human populations | ||
| 10:15 | Laura Scheinfeldt | ||
| Ancient Adaptive landscape of the human exome | ||
| 10:25 | Coffee Break | ||
| Cancer Evolution | ||
| 11:00 | Jeff Townsend | ||
| Population genetics of selection on somatic variants in cancer: identifying therapeutic targets and predicting evolution of resistance to therapy | ||
| 11:30 | Sayaka Miura | ||
| Discovering tumor clones using molecular phylogenetics | ||
| 11:50 | Vincent Cannataro | ||
| The likelihood of heterogeneity or additional mutation in KRAS or associated oncogenes to compromise targeting of oncogenic KRAS G12C | ||
| 12:00 | Kshitiz | ||
| How Evolution Of Pregnancy May Have Solved The Problem For Cancer Malignancy | ||
| 12:10 | Lunch Served | ||
| Complex Diseases | ||
| 1:30 | Joel Dudley | ||
| Using evolutionary genomics to inform precision medicine discovery | ||
| 2:00 | Li Liu | ||
| Fast Fine Mapping of Causal eQTL Variants | ||
| 2:10 | Katherine Siewert | ||
| Two Signals Of Balancing Selection Localizing With Complex Trait Loci | ||
| 2:20 | David Liberles | ||
| Context dependence of the functional effects of SNPs: a pathway simulation approach | ||
| 2:30 | Josh Akey | ||
| Signatures of recent widespread relaxation of functional constraint in protein-coding genes | ||
| 3:00 | Coffee Break | ||
| Infectious Diseases | ||
| 3:30 | Sarah Tishkoff | ||
| Evolution and Adaptation in Africa: Implications for Health and Disease | ||
| 4:00 | Ananias Escalante | ||
| Origins of Human malaria | ||
| 4:10 | Fabia Battistuzzi | ||
| Evolution of Low Complexity Regions in Plasmodium | ||
| 4:20 | Joshua P. Earl | ||
| Comparison of Two Machine Learning Techniques to Predict Virulence, and Habitat of Non-Typeable Haemophilus influenzae Via Gene Possession | ||
| 4:30 | Chase Nelson | ||
| Virus-host coevolution and carcinogenicity through the lens of human papillomavirus | ||
| . | ||
| 4:40 | Randy Nesse | ||
| Selection shapes fitness cliffs that cause disease vulnerability | ||
| 5:10 | Reception | ||
| 5:10 | Poster Session |
| September 17th, Sunday | ||
|---|---|---|
| 8:30 | Light Breakfast | ||
| 9:00 | Introduction (Sudhir Kumar) | ||
| Molecular Phylogenetics | ||
| 9:15 | Claudia Russo | ||
| Diversification of major groups of birds | ||
| 9:45 | Saitou Naruya | ||
| 30 year anniversary of the Neighbor-Joining method | ||
| 9:52 | Koichiro Tamura | ||
| RelTime: divergence time estimation under evolutionary rate variation | ||
| 9:59 | Naoko Takezaki | ||
| Resolving the Phylogenetic Position of Coelacanth: The Closest Relative Is Not Always the Most Appropriate Outgroup | ||
| 10:06 | S. Blair Hedges | ||
| Evolutionary Timetrees | ||
| 10:13 | Ruriko Yoshida | ||
| Principal Component Analysis in the Space of Phylogenetic Trees | ||
| 10:20 | Sabayasachi Das | ||
| A Phylogenetic Journey Through Adaptive Immunity | ||
| 10:27 | Kazuharu Misawa | ||
| The continuous isolation-by-distance model explains why genes mirror geography | ||
| 10:32 | Coffee Break | ||
| Functional Evolution - I | ||
| 11:03 | Wen-Hsiung Li | ||
| Evolutionary approach to functional genomics | ||
| 11:33 | Jongmin Nam | ||
| Can sea urchins find human embryonic enhancers and promoters? | ||
| 11:41 | Helen Piontkivska | ||
| Role of Host Immunity in Zika-Mediated Pathogenesis | ||
| 11:49 | Wojciech Makalowski | ||
| Evolutionary value of junk DNA | ||
| 11:57 | Zhenguo Zhang | ||
| Drosophila X-Linked Genes Have Lower Translation Rates Than Autosomal Genes | ||
| 12:05 | Shozo Yokoyama | ||
| Far-red and green color vision in the dark deep-sea | ||
| 12:13 | Nikolas Nikolaidis | ||
| Decoding the human cellular stress response | ||
| 12:21 | Lunch Served | ||
| Population Genetics | ||
| 1:31 | Aravinda Chakravarti | ||
| The molecular and population genetics of a complex disorder | ||
| 2:01 | Joaquin Dopazo | ||
| A look at the human mutational load from the systems biology perspective | ||
| 2:09 | Marcy Uyenoyama | ||
| Extending the Ewens Sampling Formula to structured populations | ||
| 2:17 | Dimitra Chalkia | ||
| Autism Spectrum Disorders: certainly complex, probably with a mitochondrial twist | ||
| 2:25 | Partha Majumder | ||
| Revisiting "Genetic Relationships between Indians and Their Neighboring Populations" Thirty-two Years Later | ||
| 2:25 | Coffee Break | ||
| Functional Evolution - II | ||
| 3:28 | George Zhang | ||
| Evolutionary adaptations to new environments generally reverse plastic phenotypic changes | ||
| 3:58 | Zhenguo Lin | ||
| Evolutionary dynamics of transcription initiation in yeasts | ||
| 4:06 | Masafumi Nozawa | ||
| Accelerated pseudogenization on the neo-X chromosome in Drosophila miranda | ||
| 4:14 | Igor Rogozin | ||
| Evolutionary switches between two serine codon series are driven by selection | ||
| 4:22 | Li Hao | ||
| Molecular epidemiology and evolutionary dynamics of Neisseria meningitidis | ||
| 4:30 | Takashi Gojobori | ||
| Comparative Marine Metagenomics with Micro-Fluidics of Single-Cell Screening | ||
| 5:00 | Nei Associates Meet in the Lobby |