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Program Schedule

September 16th, Saturday
8:30 Light Breakfast
9:00 Welcome (Sudhir Kumar)
Monogenic Diseases
9:15 Yana Bromberg Improving variant effect prediction: function, disease, and evolution of “normal”
9:45 Eduardo G. Amorim The population genetics of Mendelian diseases: the case of recessive, lethal mutations
9:55 Jinchuan Xing Investigate lysosomal disease etiology by exome sequencing
10:05 Jody Hey A new method for identifying young, harmful mutations in human populations
10:15 Laura Scheinfeldt Ancient Adaptive landscape of the human exome
10:25 Coffee Break
Cancer Evolution
11:00 Jeff Townsend Population genetics of selection on somatic variants in cancer: identifying therapeutic targets and predicting evolution of resistance to therapy
11:30 Sayaka Miura Discovering tumor clones using molecular phylogenetics
11:50 Vincent Cannataro The likelihood of heterogeneity or additional mutation in KRAS or associated oncogenes to compromise targeting of oncogenic KRAS G12C
12:00 Kshitiz How Evolution of Pregnancy May Have Solved the Problem for Cancer Malignancy
12:10 Lunch Served
Complex Diseases
1:30 Joel Dudley Using evolutionary genomics to inform precision medicine discovery
2:00 Li Liu Fast Fine Mapping of Causal eQTL Variants
2:10 Katherine Siewert Two signals of balancing selection localizing with complex trait loci
2:20 David Liberles Context dependence of the functional effects of SNPs: a pathway simulation approach
2:30 Josh Akey Signatures of recent widespread relaxation of functional constraint in protein-coding genes
3:00 Coffee Break
Infectious Diseases
3:30 Sarah Tishkoff Evolution and Adaptation in Africa: Implications for Health and Disease
4:00 Ananias Escalante Origins of Human malaria
4:10 Fabia Battistuzzi Evolution Of Low Complexity Regions In Plasmodium
4:20 Joshua P. Earl Comparison of Two Machine Learning Techniques to Predict Virulence, and Habitat of Non-Typeable Haemophilus influenzae Via Gene Possession
4:30 Chase Nelson Virus-host coevolution and carcinogenicity through the lens of human papillomavirus
.
4:40 Randy Nesse Selection shapes fitness cliffs that cause disease vulnerability
5:10 Reception
5:10 Poster Session
September 17th, Sunday
8:30 Light Breakfast
9:00 Introduction (Sudhir Kumar)
Molecular Phylogenetics
9:15 Claudia Russo Diversification of major groups of birds
9:45 Saitou Naruya 30 year anniversary of the Neighbor-Joining method
9:52 Koichiro Tamura RelTime: divergence time estimation under evolutionary rate variation
9:59 Naoko Takezaki Resolving the Phylogenetic Position of Coelacanth: The Closest Relative Is Not Always the Most Appropriate Outgroup
10:06 S. Blair Hedges Evolutionary Timetrees
10:13 Ruriko Yoshida Principal Component Analysis in the Space of Phylogenetic Trees
10:20 Sabayasachi Das A Phylogenetic Journey Through Adaptive Immunity
10:27 Kazuharu Misawa The Continuous Isolation-By-Distance Model Explains Why Genes Mirror Geography
10:32 Coffee Break
Functional Evolution - I
11:03 Wen-Hsiung Li Evolutionary approach to functional genomics
11:33 Jongmin Nam Can sea urchins find human embryonic enhancers and promoters?
11:41 Helen Piontkivska Role of Host Immunity in Zika-Mediated Pathogenesis
11:49 Wojciech Makalowski Evolutionary value of junk DNA
11:57 Zhenguo Zhang Drosophila X-Linked Genes Have Lower Translation Rates Than Autosomal Genes
12:05 Shozo Yokoyama Far-red and green color vision in the dark deep-sea
12:13 Nikolas Nikolaidis Decoding the human cellular stress response
12:21 Lunch Served
Population Genetics
1:31 Aravinda Chakravarti The molecular and population genetics of a complex disorder
2:01 Joaquin Dopazo A look at the human mutational load from the systems biology perspective
2:09 Marcy Uyenoyama Extending the Ewens Sampling Formula to structured populations
2:17 Dimitra Chalkia Autism Spectrum Disorders: certainly complex, probably with a mitochondrial twist
2:25 Partha Majumder Revisiting "Genetic Relationships between Indians and Their Neighboring Populations" Thirty-two Years Later
2:55 Coffee Break
Functional Evolution - II
3:28 George Zhang Evolutionary adaptations to new environments generally reverse plastic phenotypic changes
3:58 Zhenguo Lin Evolutionary dynamics of transcription initiation in yeasts
4:06 Masafumi Nozawa Accelerated pseudogenization on the neo-X chromosome in Drosophila miranda
4:14 Igor Rogozin Evolutionary switches between two serine codon series are driven by selection
4:22 Li Hao Molecular epidemiology and evolutionary dynamics of Neisseria meningitidis
4:30 Takashi Gojobori Comparative Marine Metagenomics with Micro-Fluidics of Single-Cell Screening
5:00 Nei Associates Meet at Lobby
September 16th, Saturday
8:30 | Light Breakfast
9:00 | Welcome (Sudhir Kumar)
Monogenic Diseases
9:15 | Yana Bromberg
Improving variant effect prediction: function, disease, and evolution of “normal”
9:45 | Eduardo G. Amorim
The population genetics of Mendelian diseases: the case of recessive, lethal mutations
9:55 | Jinchuan Xing
Investigate lysosomal disease etiology by exome sequencing
10:05 | Jody Hey
A new method for identifying young, harmful mutations in human populations
10:15 | Laura Scheinfeldt
Ancient Adaptive landscape of the human exome
10:25 | Coffee Break
Cancer Evolution
11:00 | Jeff Townsend
Population genetics of selection on somatic variants in cancer: identifying therapeutic targets and predicting evolution of resistance to therapy
11:30 | Sayaka Miura
Discovering tumor clones using molecular phylogenetics
11:50 | Vincent Cannataro
The likelihood of heterogeneity or additional mutation in KRAS or associated oncogenes to compromise targeting of oncogenic KRAS G12C
12:00 | Kshitiz
How Evolution Of Pregnancy May Have Solved The Problem For Cancer Malignancy
12:10 | Lunch Served
Complex Diseases
1:30 | Joel Dudley
Using evolutionary genomics to inform precision medicine discovery
2:00 | Li Liu
Fast Fine Mapping of Causal eQTL Variants
2:10 | Katherine Siewert
Two Signals Of Balancing Selection Localizing With Complex Trait Loci
2:20 | David Liberles
Context dependence of the functional effects of SNPs: a pathway simulation approach
2:30 | Josh Akey
Signatures of recent widespread relaxation of functional constraint in protein-coding genes
3:00 | Coffee Break
Infectious Diseases
3:30 | Sarah Tishkoff
Evolution and Adaptation in Africa: Implications for Health and Disease
4:00 | Ananias Escalante
Origins of Human malaria
4:10 | Fabia Battistuzzi
Evolution of Low Complexity Regions in Plasmodium
4:20 | Joshua P. Earl
Comparison of Two Machine Learning Techniques to Predict Virulence, and Habitat of Non-Typeable Haemophilus influenzae Via Gene Possession
4:30 | Chase Nelson
Virus-host coevolution and carcinogenicity through the lens of human papillomavirus
.
4:40 | Randy Nesse
Selection shapes fitness cliffs that cause disease vulnerability
5:10 | Reception
5:10 | Poster Session
September 17th, Sunday
8:30 | Light Breakfast
9:00 | Introduction (Sudhir Kumar)
Molecular Phylogenetics
9:15 | Claudia Russo
Diversification of major groups of birds
9:45 | Saitou Naruya
30 year anniversary of the Neighbor-Joining method
9:52 | Koichiro Tamura
RelTime: divergence time estimation under evolutionary rate variation
9:59 | Naoko Takezaki
Resolving the Phylogenetic Position of Coelacanth: The Closest Relative Is Not Always the Most Appropriate Outgroup
10:06 | S. Blair Hedges
Evolutionary Timetrees
10:13 | Ruriko Yoshida
Principal Component Analysis in the Space of Phylogenetic Trees
10:20 | Sabayasachi Das
A Phylogenetic Journey Through Adaptive Immunity
10:27 | Kazuharu Misawa
The continuous isolation-by-distance model explains why genes mirror geography
10:32 | Coffee Break
Functional Evolution - I
11:03 | Wen-Hsiung Li
Evolutionary approach to functional genomics
11:33 | Jongmin Nam
Can sea urchins find human embryonic enhancers and promoters?
11:41 | Helen Piontkivska
Role of Host Immunity in Zika-Mediated Pathogenesis
11:49 | Wojciech Makalowski
Evolutionary value of junk DNA
11:57 | Zhenguo Zhang
Drosophila X-Linked Genes Have Lower Translation Rates Than Autosomal Genes
12:05 | Shozo Yokoyama
Far-red and green color vision in the dark deep-sea
12:13 | Nikolas Nikolaidis
Decoding the human cellular stress response
12:21 | Lunch Served
Population Genetics
1:31 | Aravinda Chakravarti
The molecular and population genetics of a complex disorder
2:01 | Joaquin Dopazo
A look at the human mutational load from the systems biology perspective
2:09 | Marcy Uyenoyama
Extending the Ewens Sampling Formula to structured populations
2:17 | Dimitra Chalkia
Autism Spectrum Disorders: certainly complex, probably with a mitochondrial twist
2:25 | Partha Majumder
Revisiting "Genetic Relationships between Indians and Their Neighboring Populations" Thirty-two Years Later
2:25 | Coffee Break
Functional Evolution - II
3:28 | George Zhang
Evolutionary adaptations to new environments generally reverse plastic phenotypic changes
3:58 | Zhenguo Lin
Evolutionary dynamics of transcription initiation in yeasts
4:06 | Masafumi Nozawa
Accelerated pseudogenization on the neo-X chromosome in Drosophila miranda
4:14 | Igor Rogozin
Evolutionary switches between two serine codon series are driven by selection
4:22 | Li Hao
Molecular epidemiology and evolutionary dynamics of Neisseria meningitidis
4:30 | Takashi Gojobori
Comparative Marine Metagenomics with Micro-Fluidics of Single-Cell Screening
5:00 | Nei Associates Meet in the Lobby